Institute of Biochemistry and Molecular Medicine

People A-Z

Research Focus

My research group has a translational focus and interdisciplinary character with research priorities including both clinical research and basic science. The basic science research focuses on the role of the placenta in physiological and abnormal pregnancies. Additionally, we investigate the translational potential of placental products.

  • Schroeder M, Fuenzalida B, Yi N, Shahnawaz S, Gertsch J, Pellegata D, Ontsouka E, Leiva A, Gutiérrez J, Mueller M, Brocco MA, Albrecht C. LAT1-dependent placental methionine uptake is a key player in fetal programming of metabolic disease. Metabolism. 2024 Apr;153:155793. doi: 10.1016/j.metabol.2024.155793. Epub 2024 Jan 29. PubMed PMID: 38295946
  • Fuenzalida B, Yañez MJ, Mueller M, Mistry HD, Leiva A, Albrecht C. Evidence for hypoxia-induced dysregulated cholesterol homeostasis in preeclampsia: Insights into the mechanisms from human placental cells and tissues. FASEB J. 2024 Feb;38(2):e23431. PubMed PMID: 38265294; PubMed Central PMCID: PMC10953329
  • Barnea ER, Mueller M, Di Simone N, Inversetti A, Pacagnella R, Borovac-Pinheiro A, Nicholson W; FIGO Childbirth and Postpartum Hemorrhage Committee. Prep-for-Labor: Overview of FIGO's labor and delivery triage bundles of care to optimize maternal and newborn outcomes. Int J Gynaecol Obstet. 2023 Oct;163 Suppl 2:34-39. doi: 10.1002/ijgo.15112.PMID: 37807589
  • Spinelli M, Zdanowicz JA, Keller I, Nicholson P, Raio L, Amylidi-Mohr S, Mosimann B, Surbek D, Mueller M. Hypertensive disorders of pregnancy share common cfDNA methylation profiles. Sci Rep. 2022 Nov 18;12(1):19837. doi: 10.1038/s41598-022-24348-6. PubMed PMID: 36400896; PubMed Central PMCID: PMC9674847.
  • Fuenzalida B, Kallol S, Zaugg J, Mueller M, Mistry HD, Gutierrez J, Leiva A, Albrecht C. Primary Human Trophoblasts Mimic the Preeclampsia Phenotype after Acute Hypoxia-Reoxygenation Insult. Cells. 2022 Jun 11;11(12). doi: 10.3390/cells11121898. PubMed PMID: 35741027; PubMed Central PMCID: PMC9221019.
  • Ambrożkiewicz KA, Kozłowska U, Haesler V, Barnea ER, Mueller M, Kurpisz M. Murine glial progenitor cells transplantation and synthetic PreImplantation Factor (sPIF) reduces inflammation and early motor impairment in ALS mice. Sci Rep. 2022 Mar 7;12(1):4016. doi: 10.1038/s41598-022-08064-9. PubMed PMID: 35256767; PubMed Central PMCID: PMC8901633.
  • Spinelli M, Boucard C, Ornaghi S, Schoeberlein A, Keller I, Coman D, Hyder F, Zhang L, Haesler V, Bordey A, Barnea E, Paidas M, Surbek D, Mueller M. PreImplantation Factor modulates oligodendrocyte fate by lncRNA H19 induced de-methylation of NCOR2. JCI Insight. 2021 Oct 22;6(20). doi: 10.1172/jci.insight.132335. PubMed PMID: 34676826; PubMed Central PMCID: PMC8564895.